The feedback of experts in- and outside the XPRIZE Community, as well as our sponsors, has convinced us to move away from a focus on the immune system toward a whole-body approach to age reversal.
The winning team in this competition would demonstrate an intervention that rejuvenates several systems of the human body and reduces epigenetic age by X years (TBD).
Four systems are especially susceptible to aging:
Central nervous system
We would stipulate 3-4 relevant biomarkers for each system. Competitors would need to demonstrate a positive effect on X biomarkers in X categories to win, and reduce epigenetic age.
Our questions for you:
How many biomarkers per system would suffice?
Should competitors demonstrate age reversal in all four systems of the body?
Should rejuvenation of each system be weighted the same?
How many years of epigenetic age reversal can we (safely) ask for?