When I was thinking about an answer for other topic (the topic about “how many years of rejuvenation should bet set as a goal for the prize”), one of the reasons which made me suggest “more than 15 years” was exactly that this would allow for people TO SEE WITH THEIR OWN EYES the rejuvenation. If we set a goal of, let’s say, 7 years, it could be more feasible, but 7 years aren’t necessarily something super-obvious in terms of physical aspect. However, more than 15 years will be super-obvious. Then, the conversation about the importance of clinical trials depends of that goal: a goal of 5 or 7 years of rejuvenation makes the clinical trials way more important than a goal of more than 15 years. In fact, I think that if some entity rejuvenates people more than 15 years, an epigenetic regular measurement such as the classic Horvath epigenetic clock will be enough. Maybe a combination of epigenetic clocks could be an option.