With your input here in the community, at the lab and in two surveys, XPRIZE has been able to synthesize the following potential breakthroughs in longevity.

We now ask you to evaluate these breakthroughs and help us decide which can, and should, become XPRIZE competitions.

Why are these breakthroughs needed? How audacious are they (in terms of global impact)? What, if anything, must happen first to make these breakthroughs possible? And is anyone other than XPRIZE likely to do this?

If you believe a breakthrough has been overlooked, click on the "New Discussion" button to add one.

Welcome to the XPRIZE Longevity Community!

For much of the last century, Earth's population experienced tremendous increases in life expectancy. Is it possible to extend human lifespan even further, or reverse aging altogether?

In this initiative sponsored by Sergey Young, XPRIZE is studying the future of longevity to discover innovative and accessible ways to radically extend everyone's healthy lifespan.

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Understanding How Nutrition Affects Epigenetics

XPRIZEXPRIZE Los Angeles, CaliforniaPosts: 70 admin

A better understanding of how individuals’ epigenetics are influenced by their dietary choices.


Tools to monitor epigenetic changes (i.e. how specific genes are expressed) in individuals could help medical researchers and practitioners provide more meaningful health recommendations. The data obtained could also aid in accelerating drug development and approval. Finally, as people become more aware of the changes occuring in their bodies, they would also better understand just how desperately longevity and life extension treatments are needed.

Relevant Technologies and Techniques
  • Sensors
  • 5G internet (for data sharing)
  • Crowdsourcing (for funding and data collection)
  • Open source (for data sharing)
  • Personalization of treatments
  • Epigenetic mapping


  • NickOttensNickOttens Barcelona, SpainPosts: 288 admin
    @BruceGerman, @Karu, @AnilKumarChauhan, @sandrodemaio, you might have thoughts on this.

    This is one of the potential breakthroughs that was developed at XPRIZE's recent Future of Longevity Lab. Our objective here is to develop breakthroughs that can radically extend human life. Would this be practical? Effective? And what is the timeframe we should be thinking about for a proof of concept and for mass-scaling?
  • NickOttensNickOttens Barcelona, SpainPosts: 288 admin
    @Amy_Proulx , @Karu, @GinaQuattrochi, @Aubreymen, as food and nutrition experts, you may be interested in this discussion as well.

    It's one of the potential breakthroughs we're examining in the Longevity Community, where our goal is to identify means to radically extend human life.

    Also see the Could boosting the gut microbiome be the secret to healthier older age? discussion in this context.

    Some of our key questions here are:
    • Would this really be a breakthrough, or is it more of a gradual improvement?
    • Is anyone, other than XPRIZE, likely to work on this -- or already working on this?
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