Improving Diagnosis Tools

Many diseases aren’t diagnosed until long after they’ve had time to develop and progress in a person’s body, making them significantly more difficult to cure and ensuring they have more significant complications.

Disease diagnosis must become more efficient, affordable, and possible to perform everywhere.

@michalhemmo, @efoehr, @HRS, @rezafarivar, can you recommend (potential) breakthrough solutions for improved diagnostics?

Absolutely–and this would simultaneously enhance quality of life and reduce healthcare costs associated with advanced, complicated disease scenarios.

A breakthrough solution would be a body-transformation tracking system, consisting of (1) annual MRI examinations–whole-body plus high-resolution assessments of abdomen and brain, (2) data management system to allow for secure access to imaging data and secured, trackable sharing of data with researchers, (3) image analysis pipelines to match images over lifetime so that occurrence of malignancy or disease would be readily detected.

The key principle behind this is that each body is unique and best compared to itself–classic comparisons against “normative” sets are substantially less sensitive than a comparison to oneself. If you have a series of measurements from your body, over many years, and then something suspicious comes about, it will be much easier and far more valid to infer that a disease onset may be occurring.

What is transformation about this is that it would force a whole new field in lifespan image analysis and diagnosis.

Such a solution would need breakthroughs in MRI hardware design to drastically reduce the cost of MRI machines and make them easier to install in all facilities around the globe.

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Thank you for sharing, @rezafarivar! This sounds like the sort of breakthrough XPRIZE might be able to incentivize with a prize competition. It also meets our vision of healthcare becoming more personalized and inequities in global health being reduced and eventually eliminated.

Here’s another breakthrough idea from our Brain Trust for your feedback:

A system that can crowdsourcing diagnosis from multiple physicians, analyze and compare insights, and synthesize into a recommendation for the primary caregiver.