David Siclair’s research has demonstrated the role of epigenetics in pacing the aging process. He has even went further and asserted that if we can get a hold of the epigenomic profile at each age, we could even reverse aging.
We do have the epidenomic profile at T=0. It is the one that is evident in the egg and sperm at conception. But what about the dynamics of epigenomics? How does the embroyo develops thru multiple cell differentiation steps?
David believes that there is a vault somewhere in the cell that stores those temporal profiles and a control mechanism that applies them. If this is discovered and made to work, it certainly deserves a (Nobel) prize.
My assertion is that what we have been calling “Junk DNA” is the repository of such methylation sequences and this is a place to look for the “fountain of youth”.