While I agree in general with the first two posters’ comments/points - and I compare MSK’s comment to the search for a cure for Cancer (wherein there are now numerous ‘cures’ [effective, life-extending treatments) for many cancers, but no one “cure” because research has revealed MANY causes for cancer, and, each cancer is unique in its gene expression profile and causal chain). However, I think the development of a standard Model of Aging (like the Standard Model of Quantum Physics) is on the not-too-distant horizon…as our theories of Aging are put to the test in laboratory and Real Life experiments (and one other key development; see last paragraph).
The key thing that must happen – to begin to formulate an accurate theory and model – is to distinguish causes of Aging from (“downstream”) effects of Aging. We already know that certain genes – first discovered in Drosophila animal models – extend lifespan under certain alterations, and, that caloric restriction extends lifespan in animals (even though the human ‘analogs’ of the SIRT gene and restricted calorie diet don’t quite produce the same results as in non-human animals). But this research will lead, relatively soon, to an ‘Animal Aging Model’ (a step towards a Human Aging Model)…and from that, we will gain a predictive capability (the purpose of all animal models) that we seek.
That said, right now, based upon my reading and archival research, we are still in the discovery phase of the Science of Aging.
For example, recent work by Lloyd and Rothstein (2019) on neurodegenerative diseases has resulted in a fundamental finding (applicable to Aging): loss of functioning nucleocytoplasmic transport in neurons (which leads to a build-up of proteins in the cell cytoplasm and cell nucleus – aggregates of which produce the “plaques and tangles” noted in AD, for example). The resulting diseases (like AD, FTD, Huntington’s, and others) present the symptoms, like memory loss, we associate with Aging. These scientists and others are already experimenting with several drug candidates that target the pores in our cell nuclei to “unstick” this proteinaceous blockage and restore the normal functioning to out (brain) cell transport machinery.
Other work has found cell “reactiviation” (where otherwise cells would stop dividing and die-off) as another cellular malfunction that produces cellular and organ tissue effects associated with disease and Aging (which tend to go hand in hand, right now). No doubt additional important discoveries – and the general biological principles that underlie them – will be made, as they are now being made almost daily.
My point is that while we are eager to find a “unified theory” of Aging (and thereby have the means to put the “brakes” on Aging), and while others will always remain skeptical of any claim to a “cure for Aging” (aka “Fountain of Youth”)…we are not yet there. But, will we be there in 5 to 10 years…? Well, with the combined efects of accelerated innovation AND the implementation and integration of Artificial Intelligence in Bio-Science (e.g., robot scientists conducting millions of automated experiments in a single day)…I think so. Definitely.
[If anyone would like to read my 2013 (!) thought paper on this development – the integration of AI in the Life Sciences – please contact me and I will send you a copy]