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With your input here in the community, at the lab and in two surveys, XPRIZE has been able to synthesize the following potential breakthroughs in longevity.

We now ask you to evaluate these breakthroughs and help us decide which can, and should, become XPRIZE competitions.

Why are these breakthroughs needed? How audacious are they (in terms of global impact)? What, if anything, must happen first to make these breakthroughs possible? And is anyone other than XPRIZE likely to do this?

If you believe a breakthrough has been overlooked, click on the "New Discussion" button to add one.

Welcome to the XPRIZE Longevity Community!


For much of the last century, Earth's population experienced tremendous increases in life expectancy. Is it possible to extend human lifespan even further, or reverse aging altogether?

In this initiative sponsored by Sergey Young, XPRIZE is studying the future of longevity to discover innovative and accessible ways to radically extend everyone's healthy lifespan.

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Expedited Clinical Trials

XPRIZEXPRIZE Los Angeles, CaliforniaPosts: 65 mod
Outcome

This breakthrough would accelerate clinical trials through using constant monitoring technologies like portable diagnostics, robotics, and wearable computing elements. These devices will collect real-time data and information about participants in clinical trials, and thereby make the process of testing a treatment’s efficacy and safety much faster.

Impact

Acceleration of clinical trials would help reduce the barriers to drug discovery and testing (and thus promote accessibility). The data collected could help inform a unified theory of aging, and also the development of personalized treatments.

Relevant Technologies and Techniques
  • Sensors
  • 5G internet (for data sharing)
  • Crowdsourcing (for funding and data collection)
  • Open source (for data sharing)
  • Personalization of treatments

Comments

  • NickOttensNickOttens Barcelona, SpainPosts: 284 admin
    @rbrinton, @MarthaDeevy, @efoehr, this is one of the potential breakthroughs that was discussed at the lab. I would be interested in your take: Is this enough of a breakthrough to advance longevity? And this is unlikely to be accomplished in the absence of an XPRIZE competition?
  • efoehrefoehr Posts: 8
    Constant monitoring of thousands (maybe hundreds of thousands or millions) of people to measure aging could lay the foundation for therapies. This effort would give a deep cross section of the aging population. A longitudinal clinical trial of aging would take decades to complete. But a cross-sectional clinical study design could be completed in a few years. The key is to collect and analyze massive amounts of data across many age groups and other demographics. The regulators in USA, Europe, and Asia would need to accept this type of data as clinical proof of safety and efficacy. This constant monitoring approach could be Step One in the ultimate XPrize to find a therapy to slow the aging process.
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